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Aureobasidin A

Applications:

  • Antibiotic selection of yeast transformants

Description:

Aureobasidin A is a cyclic depsipeptide antibiotic with a molecular weight of approximately 1,100 Da. It is isolated from Aureobasidium pullulans R106. Aureobasidin A is toxic to fungi and yeast at low concentrations (0.1-0.5 μg/μL), including Saccharomyces cerevisiae, Schizosaccharomyces pombe and Candida albicans.

Limited Use Label License: [M38]

Form:

The antibiotic is supplied lyophilized, and should be reconstituted in ethanol or methanol at a stock concentration of 0.5-5.0 mg/mL. It is almost insoluble in water. Stock solutions should be stored at 4°C.

References:

  1. Takesako, K. et al. (1993) J. Antibiot. 46:1414-20.
  2. Nagiec, M.M. et al. (1995) J. Biol. Chem. 272:9809-17.

Figure Thumbnails:

Aureobasidin A TAK 9000 10 mg 276.00
Aureobasidin A TAK 9000B 5 x 10 mg 1381.00
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