Monoclonal Anti-Human Procollagen Type I C-Peptide (PIP)
Applications:
- These Products can be used to Study Collagen Synthesis by Measuring Procollagen Type I C-Peptide Levels in Cell Culture Supernatants
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Description:
Collagens (types I, II, III, IV and V) are synthesized as precursor molecules called procollagens. These contain additional peptide sequences, usually called "propeptides", at both the amino-terminal and the carboxy-terminal ends. The function of these propeptides is to facilitate the winding of procollagen molecules into a triple-helical conformation within the endoplasmic reticulum. The propeptides are cleaved off from the collagen triple helix molecule during its secretion, after which, the triple helix collagens polymerize into extracellular collagen fibrils. These Clones recognize procollagen type I C-peptide. They are suitable for the detection of non-denatured antigen released in tissue culture media and for monitoring of collagen synthesis.
Source:
- Immunogen: human procollagen type I C-peptide
- Immunized Host: BALB/c mouse
- Subclass: IgG1
- Antibody titer: 1:10,000
Form:
Lyophilized. Dissolve in 50 µL of distilled water (final conc.: 2.0 mg/mL, containing 0.1% sodium azide)
Specificity:
- These products specifically react with procollagen type I C-peptide.
- These products react with human, bovine, horse and dog antigen.
- These products do not react with rat and rabbit antigen.
Storage:
Lyophilized antibody is stable at 4°C for 2 years. The reconstituted solution can be stored at 4°C for 6 months, and at –20°C for 1 year.
Notes:
For research use only. Not for use in diagnostic or therapeutic procedures.
